This week’s newsletter covers promising CBD research for Alzheimer’s disease and leukemia, the neuroprotective power of combining CBD with antioxidants, new findings on long-term ayahuasca use and emotional resilience, and a critical look at Trump’s renewed war on drugs.
Noteworthy Read
CBD May Help Reduce Brain Inflammation Linked to Alzheimer’s Disease (Medical News Today)
A new study of mice suggests that CBD could help reduce brain inflammation linked to Alzheimer’s disease, potentially protecting neurons from damage and slowing disease progression. Researchers highlight CBD’s antioxidant and anti-inflammatory properties as key to its neuroprotective potential.
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More Noteworthy Reading
CBD Alters Gene Expression Linked to Immune Response and Cell Death in Leukemia Cells (The Marijuana Herald)
Researchers at the Stephan Angeloff Institute found that CBD exposure in leukemia cell lines triggered over 3,400 gene expression changes, including activation of tumor-suppressor and apoptosis-related genes while modulating immune and metabolic pathways—suggesting potential for future precision therapies in blood cancers.
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CBD’s Neuroprotective Effect Is Enhanced by Resveratrol and Alpha-Lipoic Acid (Frontiers in Pharmacology)
Researchers found that combining cannabidiol with antioxidant compounds resveratrol and alpha-lipoic acid amplified CBD’s ability to protect neurons and reduce oxidative stress in socially isolated animal models.
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Long-Term Ayahuasca Use Linked to Distinct Emotional Brain Activity and Higher Resilience (PsyPost)
A brain imaging study from Brazil found that long-term ayahuasca users show unique neural activity patterns and higher emotional resilience compared to nonusers, suggesting that regular ritual use may foster adaptive changes in emotional processing and stress response.
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Research Round-Up
Trump’s War on Drugs (The Intercept)
In a new Collateral Damage podcast episode, The Intercept explores how Trump’s renewed “War on Drugs” campaign revives punitive policies from the 1980s — emphasizing arrests, deportations, and border crackdowns — while critics warn it’s fueling mass incarceration and racial inequities rather than addressing addiction and public health.
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A heartfelt thank you to all the CBD brands whose generous support allows Project CBD to shine a light on the plant medicine research and reporting that matters most. We’re grateful to have you with us on this journey.
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