This week’s newsletter covers new findings on cannabis and cognitive performance in older adults, the challenges posed by semi-synthetic cannabinoids, CBD’s potential effects on bone health and fetal alcohol spectrum disorder, hemp extract’s role in reducing methamphetamine relapse, and cannabis’s link to heart arrhythmias.
Noteworthy Read
Study: Lifetime Cannabis Use Linked to Greater Cognitive Performance in Aging Populations (NORML)
A new analysis reports that older adults with a history of cannabis use performed better on several cognitive measures than matched non-users, suggesting that lifetime cannabis exposure may be associated with preserved executive function, memory, and processing speed in aging populations.
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More Noteworthy Reading
Semi-Synthetic Cannabinoids Pose Major Challenges (ScienceDirect)
This article discusses how semi-synthetic cannabinoids (i.e. designer compounds derived from modifying natural cannabinoids) present regulatory, safety, and public health challenges due to their unpredictable pharmacology and limited clinical study.
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Effects of CBD on Bone Health (MDPI)
A review suggests that CBD may support bone health by reducing inflammation and enhancing fracture healing, pointing toward potential therapeutic applications for osteoporosis and other skeletal conditions.
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CBD’s Role in Minimizing the Effects of Fetal Alcohol Spectrum Disorder (LabRoots)
This article highlights that CBD may help mitigate neurological and behavioral deficits associated with fetal alcohol spectrum disorder by reducing neuroinflammation and oxidative damage.
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Research Round-Up
CBD-Rich Hemp Extract Superior to CBD Alone in Reducing Methamphetamine-Seeking Relapse (PubMed)
In an animal study, a CBD-rich hemp extract was more effective than isolated CBD at reducing methamphetamine-seeking behavior during relapse tests, suggesting cannabis may enhance anti-addictive effects.
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Cannabis and Heart Arrhythmias (Journal of Cardiac Failure)
A Journal of Cardiac Failure article examines case reports and clinical data linking cannabis use with various heart rhythm disturbances, highlighting risk factors and the need for more rigorous research into the subject.
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A heartfelt thank you to all of the CBD brands whose generous support makes it possible for Project CBD to bring you the latest in plant medicine research and journalism each week — we couldn’t do it without you.


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