Project CBD Newsletter: Ayahuasca’s Brain Mechanisms for PTSD, CBD and Traumatic Brain Injury, Exercise and the Endocannabinoid System, Ibogaine’s Neurorestorative Properties, and Hemp Microgreens as Superfood

Project CBD Newsletter: Ayahuasca's Brain Mechanisms for PTSD, CBD and Traumatic Brain Injury, Exercise and the Endocannabinoid System, Ibogaine's Neurorestorative Properties, and Hemp Microgreens as Superfood
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This week’s newsletter covers groundbreaking research on ayahuasca’s effects on PTSD-related brain circuits, CBD’s potential for traumatic brain injury recovery, the endocannabinoid system’s role in exercise-induced depression protection, ibogaine’s neurorestorative properties, and the nutritional promise of hemp microgreens.

Noteworthy Read

Scientists Identify Brain Mechanism Behind Ayahuasca’s PTSD Benefits (PsyPost)

New research suggests ayahuasca may help ease PTSD symptoms by altering activity in brain circuits tied to fear processing and emotional memory. The findings present an opportunity to better understand how psychedelic experiences might help the brain release entrenched trauma and create space for new emotional responses.

Read moreView more in Psychedelics

More Noteworthy Reading

CBD & Brain Injury: CBD’s Effect on TBI-Related Neuronal Damage Pathways (ScienceDirect)

Researchers are exploring how CBD may help protect the brain after traumatic injury by calming inflammatory signals, reducing oxidative stress, and supporting cellular repair pathways. Early findings suggest CBD could play a role in helping the brain recover from trauma and maintain healthier neural function over time.

Read moreView more in CBD

The Endocannabinoid System Facilitates Exercise-Induced Protection Against Major Depressive Disorder (Frontiers in Psychiatry)

A study from China suggests that the body’s endocannabinoid system may help explain why regular exercise protects against depression. Physical activity appears to activate this internal signaling system, which helps regulate mood, stress resilience, and emotional balance — highlighting the natural connection between movement, brain chemistry, and mental well-being.

Read moreView more in Endocannabinoid System

Research Round-Up

Neurorestorative Properties of Ibogaine (PubMed)

A scientific review highlights how ibogaine may support brain repair by promoting neuroplasticity — the brain’s ability to form new connections — while also influencing pathways involved in addiction and emotional regulation. These effects may help explain why the compound has drawn attention as a potential tool for addiction recovery and psychological healing.

Read moreView more in Psychedelics

Superfood: Finola Hemp Microgreens (MDPI)

Researchers examined the nutritional profile of Finola hemp microgreens and found them to be rich in beneficial fatty acids, antioxidants, and plant proteins. The findings suggest these young hemp sprouts could serve as a nutrient-dense addition to diets focused on whole-food, plant-based wellness.

Read moreView more in CBD

A heartfelt thank you to all the CBD brands whose generous support fuels Project CBD’s mission to bring you the latest in plant medicine research — we couldn’t do this work without you.



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